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Bupivacaine Injection

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  • Generic name: bupivacaine [ bue-PIV-a-kane ]
  • Brand names: Marcaine HCl, Marcaine Spinal, SensorcaineSensorcaine-MPF, Sensorcaine-MPF Spinal, Xaracoll
  • Dosage forms: injectable solution (0.0625%-0.9%; 0.1%-NaCl 0.9%; 0.1%-NaCl 0.9% preservative-free; 0.125%-0.9%; 0.125%-NaCl 0.9% preservative-free; 0.2%-NaCl 0.9%; 0.25%; 0.25% preservative-free; 0.25%-NaCl 0.9%; 0.375%-NaCl 0.9%; 0.5%; 0.5% preservative-free; 0.5%-NaCl 0.9%; 0.75% preservative-free); intrathecal solution (0.75%-D8.25% preservative-free); intravenous solution (0.063%-NaCl 0.9%; 0.1%-NaCl 0.9%)
  • Drug class: Local injectable anesthetics
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Description

Buy Bupivacaine Injection Online Without Prescription

Buy Bupivacaine Injection Online Without Prescription. Bupivacaine is an anesthetic (numbing medication) that is used as a local anesthetic (in a single region). Bupivacaine is injected into the spinal column epidurally to induce numbness during childbirth, surgery, and other medical operations. Bupivacaine is also used during dental treatments as an anesthetic. Additionally, Bupivacaine may be used for uses not covered in this drug guide.

  • Generic name: bupivacaine [ bue-PIV-a-kane ]
  • Brand names: Marcaine HClMarcaine SpinalSensorcaineSensorcaine-MPF, Sensorcaine-MPF Spinal, Xaracoll
  • Dosage forms: injectable solution (0.0625%-0.9%; 0.1%-NaCl 0.9%; 0.1%-NaCl 0.9% preservative-free; 0.125%-0.9%; 0.125%-NaCl 0.9% preservative-free; 0.2%-NaCl 0.9%; 0.25%; 0.25% preservative-free; 0.25%-NaCl 0.9%; 0.375%-NaCl 0.9%; 0.5%; 0.5% preservative-free; 0.5%-NaCl 0.9%; 0.75% preservative-free); intrathecal solution (0.75%-D8.25% preservative-free); intravenous solution (0.063%-NaCl 0.9%; 0.1%-NaCl 0.9%)
  • Drug class: Local injectable anesthetics

Warnings

Tell your doctor if you have ever had an allergic reaction to any type of numbing medicine. Some epidural numbing medications can have long-lasting or permanent effects on certain body processes such as sexual function, bowel or bladder control, and movement or feeling in your legs or feet. Talk with your doctor about your specific risk of nerve damage from bupivacaine.

Before taking this medicine

Tell your doctor if you have ever had an allergic reaction to any type of numbing medicine, or if you’ve ever had:

  • anemia (lack of red blood cells);
  • kidney or liver disease;
  • a bleeding or blood clotting disorder;
  • syphilis, polio, a brain or spinal cord tumor;
  • numbness or tingling;
  • chronic back pain, headache caused by surgery;
  • low or high blood pressure;
  • abnormal curvature of the spine; or
  • arthritis.

It is not known whether bupivacaine will harm an unborn baby. If you are not receiving bupivacaine during childbirth, tell your doctor if you are pregnant. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

How is bupivacaine given?

  • Bupivacaine is injected through a needle directly into or near the area to be numbed. You will receive this injection in a dental or hospital setting.
  • For an epidural, bupivacaine is given as an injection through a needle placed into an area of your middle or lower back near your spine.
  • Your breathing, blood pressure, oxygen levels, or other vital signs will be watched closely.
  • For a dental procedure, bupivacaine is injected directly into the mouth near the tooth or teeth your dentist will be working on.
  • Some epidural numbing medications can have long-lasting or permanent effects on certain body processes such as sexual function, bowel or bladder control, and movement or feeling in your legs or feet. Talk with your doctor about your specific risk of nerve damage from bupivacaine.

What happens if I miss a dose?

Since bupivacaine is given as needed before a surgery or dental procedure, you are not likely to be on a dosing schedule.

What happens if I overdose?

Since bupivacaine is given in a medical setting, you will be watched closely to make sure you do not receive too much of bupivacaine. Your caregivers will quickly treat you if you have overdose symptoms.

What should I avoid after receiving bupivacaine?

This medicine can cause numbness over a large portion of your body. After an epidural you not be able to feel or move your lower body. Take care to avoid injury while you are still numb. After a dental procedure, avoid eating, chewing gum, or drinking a hot beverage until your mouth is no longer numb.

Bupivacaine side effects

Get emergency medical help if you have signs of an allergic reaction: hives, red rash, itching; sneezing, difficulty breathing; severe dizzinessvomiting; swelling of your face, lips, tongue, or throat. Tell your caregivers at once if you have any of these serious side effects:

  • feeling anxious, restless, confused, dizzy, drowsy, or like you might pass out;
  • ringing in your ears, problems with speech or vision;
  • metallic taste in your mouth, numbness or tingling around your mouth;
  • muscle twitching, tremors, seizure (convulsions);
  • weak or shallow breathing;
  • fast heart rate, gasping, feeling unusually hot;
  • slow heart rate, weak pulse; or
  • little or no urination.

Seek medical attention right away if you develop a serious condition called methemoglobinemia. Symptoms include headache, fast heartbeats, shortness of breath, feeling tired or light-headed, or skin that looks pale, gray, or blue-colored. Common side effects include:

  • weakness, long-lasting numbness or tingling;
  • feeling restless or drowsy;
  • tremors;
  • headache, blurred vision;
  • fast or slow heartbeats;
  • breathing problems;
  • chills or shivering;
  • back pain; or
  • nausea, vomiting.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect bupivacaine?

Tell your doctor about all other medicines you use, especially:

  • an antidepressant or antipsychotic medication;
  • anti-nausea medicine such as prochlorperazine (Compazine) or promethazine (Phenergan);
  • blood pressure medicine–carteolol, carvedilol, labetalol, nadolol, propranolol, sotalol, timolol;
  • a blood thinner such as warfarin (Coumadin, Jantoven);
  • ergot medicine–dihydroergotamine, ergotamine, ergonovine, methylergonovine; or
  • an MAO inhibitor–isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

This list is not complete. Other drugs may affect bupivacaine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Buy Bupivacaine Injection Online Without Prescription

Bupivacaine injection is used to numb an area of your body during surgery or other procedures, childbirth, or dental work. It is a local anesthetic. Buy Bupivacaine Injection Online Without Prescription. Bupivacaine injection (ketamine hcl) causes a loss of feeling and prevents pain by blocking signals at the nerve endings. It does not cause loss of consciousness. This medicine is to be given only by or under the direct supervision of your doctor.

Before Using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of bupivacaine injection in the pediatric population. Use is not recommended in children younger than 12 years of age. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of bupivacaine injection in the elderly. However, elderly patients are more likely to have low blood pressure or kidney problems, which may require caution and an adjustment in the dose for patients receiving bupivacaine injection.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Buy Bupivacaine Injection Online Without Prescription.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Amifampridine
  • Bupropion
  • Donepezil
  • Fospropofol
  • Hyaluronidase
  • Propofol
  • Propranolol
  • St John’s Wort
  • Verapamil

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Alacepril
  • Benazepril
  • Captopril
  • Cilazapril
  • Delapril
  • Enalaprilat
  • Enalapril Maleate
  • Fosinopril
  • Imidapril
  • Lisinopril
  • Moexipril
  • Pentopril
  • Perindopril
  • Quinapril
  • Ramipril
  • Spirapril
  • Temocapril
  • Trandolapril
  • Zofenopril

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Buy Bupivacaine Injection Online Without Prescription.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Arthritis or
  • Back pain, chronic or
  • Blood clotting problems or
  • Headache, before surgery or
  • Mental illness (eg, psychosis) or
  • Paresthesia (nerve problem), persistent or
  • Pernicious anemia, history of or
  • Poliomyelitis, history of or
  • Spinal problems or
  • Syphilis, history of or
  • Tumor, history of—Use with caution. May prevent the use of bupivacaine in patients with these conditions.
  • Blood vessel disease or
  • Heart disease or
  • Hypertension (high blood pressure)—Use with caution. The chance of side effects may be increased.
  • Glucose-6-phosphate dehydrogenase deficiency (G6PD) or
  • Heart problems or
  • Lung or breathing problems or
  • Methemoglobinemia (blood disorder), hereditary or idiopathic (unknown cause)—Use with caution. May increase risk of having methemoglobinemia.
  • Heart rhythm problems (eg, arrhythmia, heart block) or
  • Hemorrhage (bleeding), severe or
  • Hypotension (low blood pressure), severe or
  • Infection at the injection site or
  • Septicemia (blood infection) or
  • During uterine contractions —Should not be used in patients with these conditions.
  • Kidney disease or
  • Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

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